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Health

Scientists discover how HIV kills immune cells
Will the new discovery help find the cure?
 
Published Wednesday, June 12, 2013
by Amanda Raymond

Researchers at the National Institute of Allergy and Infectious Diseases have made a historic discovery about the way HIV kills immune cells.

It is common knowledge that HIV infects and kills cells in the human body that fight off infection, but until now scientists did not know how.

“What this study does for the first time, in now more than 30 years of study, is show that it’s a precise molecular triggering signal that causes the cell to die,” said Anthony Fauci M.D., director of NIAID, which is part of the National Institutes of Health.

HIV replicates inside immune cells through a process that includes putting its genes into the cell’s DNA. Scientists have learned that during this process, an enzyme is activated and does something out of the ordinary. Instead of putting the strands of DNA back together, the enzyme puts out a signal that tells the immune cell to die. That kills the very cells that are supposed to fight the infection.

All of this means that researchers have a target. They can now work on developing more treatments that focus on the early replication of the disease. The key is to stop HIV from working itself into the DNA of immune cells and ending HIV’s activation of the enzyme. Doing this will stop HIV from gaining strength and killing off the infection-fighting cells.

Fauci said treatments like those are already accessible to the public.

“We already have drugs that actually can block the ability of the viral DNA to integrate itself into the cell DNA. So, it really is the molecular explanation for something that we’ve been observing for a long time,” he said. “Whether or not it will have any practical applicability in the reasonable future is very difficult to predict.”

This discovery can also answer why HIV-infected cells can lay dormant and can continually cause problems for those infected.

Fauci explained that this discovery is about understanding HIV more than anything else.

“This is a very important incremental step on the way to understanding more about HIV,” Fauci said. “And the more that you understand, the better chance you have to develop countermeasures to block that, be it in a vaccine, or be it in a new drug or be it in a way to preserve cells from getting killed.

Comments

Hi, I work in a communication company I want to share my testimony to the world, my name is maria katrina, i am from united kingdom in belfast north ireland, I was a stripper in a club I got effected with HIV due to the nature of my job, In april 15 2013 i was tested positive to HIV, This is not design to convince you but its just a personal health experience . I never taught doctor hakim could ever get my HIV-AIDS cured with his healing herb spell, i have tried almost everything but I couldn't find any solution on my disease, despite all these happening to me, i always spend a lot to buy a HIV drugs from hospital and taking some several medications but no relieve, until one day i was just browsing on the internet when i came across a great post of !Michelle! who truly said that she was been diagnose with HIV and was healed that very week through the help of this great powerful healing spell doctor ,I wonder why he is called the great papa hakim, i never knew it was all because of the great and perfect work that he has been doing that is causing all this. so I quickly contacted him, and he ask me some few questions and so i did all the things he asked me to do,He ask me to buy some herbs and which I did for my cure,only to see that at the very day which he said i will be healed, all the strength that has left me before rush back and i becomes very strong and healthy, this disease almost kills my life all because of me, so i went to hospital to give the final test to the disease and the doctor said i am HIV negative, i am very amazed and happy about the healing doctor hakim gave to me from the ancient part of africa, you can email him now for your own healing too on his email: dr.hakimherbalspellworld@gmail.com
Posted on August 16, 2013
 

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